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Single-layer Cartridge Filter(MCE 0.2μm)

Product Introduction

Alioth Aligard® MHF Single-layer Cartridge Filter is made from mixed cellulose ester. It has a nominal filtration accuracy of 0.2 μm, a sturdy structure and stable material. It can efficiently retain pollutants, effectively remove particles and colloidal contaminants, block no important active ingredients, protect downstream filtration equipment, and prevent premature clogging.


Product Properties

  • Fast flow rate
  • High capacity
  • No fiber release
  • Can withstand multiple cycles of high-temperature sterilization


Typical Applications

  • Pre-filtration of culture media and buffer solutions
  • Pre-filtration of LVP/SVP
  • Pre-filtration of blood products
  • Pre-filtration for column protection, etc.


Flow Characteristics

This filter is produced in a controlled environment, and its manufacturing process conforms to ISO9001 quality system standards. Each filter undergoes an integrity testing during the process of manufacturing.


Product Characteristics

Size (i.e., length) 10 inch / 20 inch / 30 inch
Structural Materials

Filter membrane:Mixed Cellulose Ester

Supporting layer:Polypropylene


Cartridge body and end caps:Polypropylene


Pore size 0.2 μm
Filtration area 10 inch 0.68 m2 / 20 inch 1.32 m2/ 30 inch 2.04 m2
Maximum tolerated differential
pressure during operation
Forward: 5 bar ( 72.5 psi ) @ 25℃ / 1.5 bar ( 21.75 psi ) @ 80℃ / Reverse: 2 bar ( 29 psi ) @ 25℃
Sterilization parameters 121℃, 30 minutes, 5 cycles of high-pressure sterilizations or 5 cycles of sterilization in place
24-hour dynamic leaching
Water: ~20 mg / 10 inch
Ethanol: water ( 50:50 ): ~55 mg / 10 inch
Biological safety All the construction components of this cartridge comply with the requirements for biological safety of Class VI plastics in current USP < 88 >
Indirect food additive The primary construction components of this cartridge comply with the reguirements for food contact materials as stipulated in EU 1935 / 2004 / EC and FDA 21 CFR 177-182
Cleanliness Cleanliness meets the requirements for nonfiber releasing filter as specified in FDA 21 CFR 211.72 and 210.3 (b) (5) (6), and the level of insoluble particles in rinsing liquid meets the
requirements of USP < 788 >
Endotoxin The endotoxin level of cartridge rinsing liquid is < 0.25 EU/mL as indicated by gel method, which complies with the requirements of USP < 85 >
Integrity Each filter has passed the integrity test
Manufacturing environment All filters are manufactured in a Class 100,000 clean workshop
TOC / Conductivity TOC < 0.5 mg/L, Conductivity < 1.3 μS/cm


Ordering Information

For further information, please contact us and Alioth technical team will provide a comprehensive service for your filtration process.