Home  ꄲ  除菌级过滤  ꄲ  PES 0.45+0.2 μm Sterilizing-Grade Capsule Filters
囊式CHC@3x
넳 넲

PES 0.45+0.2 μm Sterilizing-Grade Capsule Filters

Product Introduction
Alioth Alipore® CHC double-layer polyethersulfone (PES) filters are suitable for a variety of sterile filtration of process fluids with both cartridge and disposable capsule format available. The filter has passed strict sterilization performance validation. It features a built-in pre-filtration layer to achieve high flow rate and capacity, and thereby optimize your process efficiency and cost effectiveness.

Data Download：

Depth Stacked DataSheet
넳 넲

  • 我是段落。点击这儿添加你的文字并编辑它，非常容易。-双击进行编辑

     

    • Highly asymmetric Double-layer PES membrane.

    • High flux and increased capacity.

    • Validated reliable bacterial retention.

    • Wide chemical compatibility (pH 1-14).

    • 100% integrity tested.

     

  •  

    • Buffers

    • Final Fill

    • Cell Culture Media

    • Process Intermediates

    • Water for pharmaceutical process

     

  • Product Specifications—Alicap L-type Capsule Filter

    Product Specification Alicap L300 Alicap L600 Alicap L02 Alicap L04 Alicap L5 Alicap L10
    Dimensions
    Body Diameter
    Maximum Width
    Maximum Length

     

    67 mm
    77 mm
    100.5 mm

     

    67 mm
    77 mm
    122 mm

     

    72 mm
    96 mm
    164 mm

     

    72 mm
    96 mm
    217 mm

     

    107 mm
    147 mm
    224 mm

     

    107 mm
    147 mm
    362 mm
    Filtration Area 230 cm2 430 cm2 0.11 m2 0.19 m2 0.3 m2 0.6 m2
    Pore Size 0.45+0.2 μm
    Materials of
    Construction

    Filter membrane: Hydrophilic polyethersulfone (PES)

    Supporting Layer: Polypropylene
    O-rings of capsules vent: Silicone

    Liner / Cartridge body / End caps / Housing: Polypropylene
    Bacterial Retention ＞107 cfu /cm2 B. diminuta ( ATCC® 19146TM )
    Maximum Differential
    Pressure    		 Forward: 5.0 bar（72.5 psi）@ 25°C / 3.0 bar（43.5 psi）@ 80°C
    Reverse: 2.0 bar（29.0 psi）@25℃
    Bubble Point ≥3520 mbar（51 psi）(wetted with H2O, 20℃, compressed air）
    Diffusion Through a water wet membrane at 2760 mbar (40 psi) （20℃, compressed air ）
    - ≤2.5 mL/min ≤5.5 mL/min ≤9.5 mL/min ≤12.5 mL/min ≤25 mL/min
    Sterilization Autoclave(A&G): 131℃, 30min, 3 cycles
    Gamma-compatible (G): 45 kGy
    *Cannot be steam sterilized in-line, Pre-sterilized capsule filters must not be re-sterilized    		 Autoclave(A&G): 131℃, 30min, 5 cycles
    Gamma-compatible (G): 45 kGy
    *Cannot be steam sterilized in-line, Presterilized capsule filters must not be re-sterilized
    Biological Safety All the construction components of this filter comply with the requirements for biological safety of Class VI plastics in current USP <88>
    Indirect Food Additive The primary construction components of this filter comply with the requirements for food contact materials as stipulated in EU 1935 / 2004 / EC and FDA 21 CFR 177-182
    Cleanliness Cleanliness meets the requirements for nonfiber releasing filter as specified in FDA 21 CFR211.72 and 210.3 (b) (5) (6), and the level of insoluble particles in rinsing liquid meets the requirements of USP <788>
    Endotoxin The endotoxin level of cartridge rinsing liquid is <0.25 EU/mL as indicated by gel method, which complies with the requirements of USP <85>
    TOC / Conductivity Filtrate of this filter , TOC＜0.5 mg/L, Conductivity＜1.3 μS/cm
    Integrity Filters are 100% integrity tested
    Manufacturing
    Environment    		 Manufactured in conformance with cGMP

     

    Typical Flow Characteristics

    Water Flow Rate and Pressure Drop -Alipore® CHC 0.45+0.2μm Cartridge Filters

    Water Flow Rate and Pressure Drop-Alioth Alipore® CHC 0.45+0.2μm Alicap L-type Capsule Filter

    （KFBEC52M3**S1*）

    *T1, T3, B5, B7 represent different interface types, see order information for details.