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囊式CHC@3x
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Sterilizing-Grade Capsule Filter(PES 0.45+0.2 μm)

Product Introduction

Alioth Alipore® CHC double-layer polyethersulfone (PES) filters are suitable for a variety of sterile filtration of process fluids with both cartridge and disposable capsule format available. The filter has passed strict sterilization performance validation. It features a built-in pre-filtration layer to achieve high flow rate and capacity, and thereby optimize your process efficiency and cost effectiveness.

 

Key Features and Benefits

  • Highly asymmetric Double-layer PES membrane
  • High flux and increased capacity
  • Validated reliable bacterial retention
  • Wide chemical compatibility (pH 1-14)
  • 100% integrity tested

 

Typical Applications

  • Buffers
  • Final Fill
  • Cell Culture Media
  • Process Intermediates
  • Water for pharmaceutical process

 

Typical Flow Characteristics

Water Flow Rate and Pressure Drop -Alipore® CHC 0.45+0.2μm Cartridge Filters

Water Flow Rate and Pressure Drop-Alioth Alipore® CHC 0.45+0.2μm Alicap L-type Capsule Filter

（KFBEC52M3**S1*）

*T1, T3, B5, B7 represent different interface types, see order information for details.

 

Product Specifications—Alicap L-type Capsule Filter

Product Specification Alicap L300 Alicap L600 Alicap L02 Alicap L04 Alicap L5 Alicap L10
Dimensions
Body Diameter
Maximum Width
Maximum Length

 

67 mm
77 mm
100.5 mm

 

67 mm
77 mm
122 mm

 

72 mm
96 mm
164 mm

 

72 mm
96 mm
217 mm

 

107 mm
147 mm
224 mm

 

107 mm
147 mm
362 mm
Filtration Area 230 cm2 430 cm2 0.11 m2 0.19 m2 0.3 m2 0.6 m2
Pore Size 0.45+0.2 μm
Materials of
Construction

Filter membrane: Hydrophilic polyethersulfone (PES)

Supporting Layer: Polypropylene
O-rings of capsules vent: Silicone

Liner / Cartridge body / End caps / Housing: Polypropylene
Bacterial Retention ＞107 cfu /cm2 B. diminuta ( ATCC® 19146TM )
Maximum Differential
Pressure		 Forward: 5.0 bar（72.5 psi）@ 25°C / 3.0 bar（43.5 psi）@ 80°C
Reverse: 2.0 bar（29.0 psi）@25℃
Bubble Point ≥3520 mbar（51 psi）(wetted with H2O, 20℃, compressed air）
Diffusion Through a water wet membrane at 2760 mbar (40 psi) （20℃, compressed air ）
- ≤2.5 mL/min ≤5.5 mL/min ≤9.5 mL/min ≤12.5 mL/min ≤25 mL/min
Sterilization Autoclave(A&G): 131℃, 30min, 3 cycles
Gamma-compatible (G): 45 kGy
*Cannot be steam sterilized in-line, Pre-sterilized capsule filters must not be re-sterilized		 Autoclave(A&G): 131℃, 30min, 5 cycles
Gamma-compatible (G): 45 kGy
*Cannot be steam sterilized in-line, Presterilized capsule filters must not be re-sterilized
Biological Safety All the construction components of this filter comply with the requirements for biological safety of Class VI plastics in current USP <88>
Indirect Food Additive The primary construction components of this filter comply with the requirements for food contact materials as stipulated in EU 1935 / 2004 / EC and FDA 21 CFR 177-182
Cleanliness Cleanliness meets the requirements for nonfiber releasing filter as specified in FDA 21 CFR211.72 and 210.3 (b) (5) (6), and the level of insoluble particles in rinsing liquid meets the requirements of USP <788>
Endotoxin The endotoxin level of cartridge rinsing liquid is <0.25 EU/mL as indicated by gel method, which complies with the requirements of USP <85>
TOC / Conductivity Filtrate of this filter , TOC＜0.5 mg/L, Conductivity＜1.3 μS/cm
Integrity Filters are 100% integrity tested
Manufacturing
Environment		 Manufactured in conformance with cGMP


Ordering Information

Alicap L-type Capsule Filter

 

 

For further information, please contact us and Alioth technical team will provide a comprehensive service for your filtration process.

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